Anti Depressants

Calan (Verapamil)

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Calan (Verapamil) is a calcium channel blocker used to treat angina (chest pain) or high blood pressure. It is also used to treat and prevent a rapid heart rate.

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About Calan (Verapamil):

Product Type: Blood Pressure

Brand name: Calan Generic name: Verapamil What is the most important information I should know about Calan? • Do not stop taking this medication without first talking to your doctor. If you stop taking the medication your condition could become worse. • Do not crush chew or break extended-release forms of Calan such as generic Covera-HS and Verelan PM. Swallow them whole. Generic Calan SR Isoptin SR and Calan SR may be divided in half but should not be crushed or chewed. What is Calan? • Calan is in a class of drugs called calcium channel blockers. Calan relaxes (widens) blood vessels (veins and arteries) which makes it easier for the heart to pump and reduces its workload. • Calan is used to treat hypertension (high blood pressure) to treat angina (chest pain) and to control some types of irregular heartbeats. • Calan may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Calan? • Before taking this medication tell your doctor if you have kidney or liver disease; other diseases of the heart or blood vessels such as sick sinus syndrome aortic stenosis heart failure heart block Wolff-Parkinson-White syndrome coronary artery disease or low blood pressure; or muscular dystrophy. • You may not be able to take Calan or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. • Calan is in the FDA pregnancy category C. This means that it is not known whether Calan will be harmful to an unborn baby. Do not take Calan without first talking to your doctor if you are pregnant or could become pregnant during treatment. • Calan passes into breast milk and may harm a nursing infant. Do not take Calan without first talking to your doctor if you are breast-feeding a baby. How should I take Calan? • Take Calan exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • Verelan Verelan PM Calan Isoptin Covera-HS and generic forms of regular-release Calan can be taken with or without food. Taking the medication with food may reduce stomach upset if it occurs. • Calan SR Isoptin SR and generic sustained-release Calan (Calan SR) may be more likely to cause stomach upset and should be taken with food to reduce this side effect. • Take Covera-HS and Verelan PM at bedtime. • If you have trouble swallowing the Verelan pellet-filled capsules they can be opened and the contents can be sprinkled onto cold soft food such as applesauce. This mixture must be swallowed without chewing. Use the mixture immediately. Do not save it for later use. (Do not use this procedure for the Verelan PM capsules.) • Do not crush chew or break extended-release forms of Calan such as Covera-HS and Verelan PM. Swallow them whole. Generic Calan SR Isoptin SR and Calan SR may be divided in half if the tablets are scored but should not be crushed or chewed. • If you are taking Covera-HS do not be concerned if you find what looks like an undissolved tablet in your stool. This medication is formulated with an outer shell that does not dissolve. This shell allows the medicine to be released slowly into your body before it is passed out in the stool. • It is important to take Calan regularly to get the most benefit. • Do not stop taking this medication without first talking to your doctor. If you stop taking the medication your condition could become worse. • Grapefruit and grapefruit juice may interact with Calan. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Your doctor may want you to have blood tests blood pressure monitoring or other medical evaluations during treatment with Calan to monitor progress and side effects. • Store Calan at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However if it is almost time for the next dose skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Calan overdose include dizziness weakness chest pain shortness of breath fainting an unusually fast or slow heartbeat coma slurred speech and confusion. What should I avoid while taking Calan? • Grapefruit and grapefruit juice may interact with Calan. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Avoid the use alcohol. Alcohol may further lower blood pressure and increase drowsiness and dizziness while taking Calan. • Follow any recommendations your doctor makes about diet or exercise. What are the possible side effects of Calan? • If you experience any of the following serious side effects stop taking Calan and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); an unusually fast or slow heartbeat; shortness of breath (heart failure); fainting; abnormal behavior or psychosis; jaundice (yellowing of the skin or eyes); or swelling of the legs or ankles. • Other less serious side effects may be more likely to occur. Continue to take Calan and talk to your doctor if you experience unusual headache fatigue or tiredness; insomnia or trouble sleeping; vivid dreams; hair loss; nausea or diarrhea; or increased urination. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Calan? • Before taking this medication tell your doctor if you are taking any of the following drugs: cyclosporine (Sandimmune Neoral); cimetidine (Tagamet Tagamet HB); carbamazepine (Tegretol Carbatrol); lithium (Lithobid Eskalith others); theophylline (Theo-Dur Theochron Theolair Theobid Elixophyllin Slo-Phyllin others); rifampin (Rifadin Rimactane); phenobarbital (Luminal Solfoton); an HMG CoA reductase inhibitor such as atorvastatin (Lipitor) lovastatin (Mevacor) simvastatin (Zocor) and others; or another heart medication such as propranolol (Inderal) metoprolol (Lopressor Toprol XL) atenolol (Tenormin) digoxin (Lanoxin) quinidine (Quinora Quinidex Quinaglute) flecainide (Tambocor) disopyramide (Norpace) captopril (Capoten) enalapril (Vasotec) and others. • You may not be able to take Calan or you may require a dosage adjustment or special monitoring if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Calan or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins minerals and herbal products

Generic Calan (Verapamil)

Calaptin Apo-Verap Arpamyl Berkatens Cardiagutt Cardibeltin Cordilox Covera-HS Dignover Dilacoran Drosteakard Geangin Iproveratril Isoptimo Isoptin NU-Verap Novo-Veramil Quasar Securon Univer Vasolan Veracim Veramex Veraptin Verelan Verexamil

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What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. 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Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Store Anafranil at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Anafranil overdose include seizures confusion drowsiness agitation hallucinations and low blood pressure (dizziness fatigue fainting). What should I avoid while taking Anafranil? • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. 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What are the possible side effects of Anafranil? • If you experience any of the following serious side effects stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips face or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision severe headache); difficulty urinating; or fever with increased sweating muscle stiffness or severe muscle weakness. • Other less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience drowsiness or dizziness; dry mouth and eyes; constipation; mild tremor; sweating; mild agitation weakness or headache; ringing in the ears; nausea; or loss of weight or appetite. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. 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