Anti Depressants

Epivir (Lamivudine)

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Epivir (Lamivudine) is a nucleoside analogue used with other medicines (such as zidovudine or ritonavir) to treat Human Immunodeficiency Virus infection (HIV).

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About Epivir (Lamivudine):

Product Type: Anti Viral

Brand name: Epivir Generic name: Lamivudine What is the most important information I should know about Epivir? • Before taking Epivir tell your doctor if you have kidney disease liver disease a pancreas disorder or problems with your muscles. • Call your doctor at once if you have liver problems while you are using Epivir. Symptoms to watch for include stomach pain nausea and vomiting low fever lost appetite dark urine clay-colored stools or jaundice (yellowing of the skin or eyes). • If you have hepatitis B you may develop liver symptoms after you stop taking Epivir even months after stopping. Your doctor may want to check your liver at regular visits for several months after you stop using this medication. Do not miss any scheduled visits. • Swelling of the pancreas (pancreatitis) may occur during treatment especially in children using Epivir. Call your doctor right away if you notice any of these symptoms of pancreatitis: sudden and severe pain in the upper middle or left side of your stomach nausea and/ or vomiting fever chills rapid pulse or stomach pain that gets worse after eating or when lying down flat. • Call your doctor at once if you have muscle pain or weakness numbness or tingling in any part of your body and nausea with vomiting. These could be signs of lactic acidosis. • Epivir tablets and liquid contain a higher dose of Epivir than Epivir-HBV. Epivir is for treating HIV and Epivir-HBV is for treating hepatitis B. Each time you get a refill of this medication be sure you have received the correct brand to treat your condition. What is Epivir? • Epivir is an antiviral medication. It is in a group of human immunodeficiency virus (HIV) medicines called reverse transcriptase inhibitors. Epivir helps keep the HIV virus from reproducing in the body. • The Epivir brand of Epivir is used to treat HIV which causes the acquired immunodeficiency syndrome (AIDS). Epivir is not a cure for HIV or AIDS. The Epivir-HBV brand of Epivir is used to treat chronic hepatitis B. • Epivir may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Epivir? • Before taking Epivir tell your doctor if you have: kidney disease; liver disease; pancreatitis; or problems with your muscles. • If you have any of the conditions listed above you may not be able to use Epivir or you may need a dosage adjustment or special tests during treatment. • If you have hepatitis B you may develop liver symptoms after you stop taking Epivir even months after stopping. Your doctor may want to check your liver at regular visits for several months after you stop using this medication. Do not miss any scheduled visits. • If you have diabetes you should know that the liquid forms of this medication contain 3 to 4 grams of sucrose (sugar) per dose. • Epivir is in the FDA pregnancy category C. This means that it is not known if it will be harmful to an unborn baby. Do not use this medication without telling your doctor if you are pregnant. It is very important to treat HIV/ AIDS during pregnancy to reduce the risk of infecting the baby. Tell your doctor if you become pregnant during treatment. • It is not known if Epivir passes into breast milk or if it could harm a nursing baby. Women with HIV or AIDS should not breast-feed. Even if your baby is born without HIV you may still pass the virus to the baby in your breast milk. How should I take Epivir? • Take this medication exactly as your doctor has prescribed it for you. Do not use more of the medication than recommended. Do not take Epivir for longer than your doctor has prescribed. • To be sure you get the correct dose measure the liquid with a marked measuring spoon or medicine cup not with a regular table spoon. If you do not have a dose-measuring device ask your pharmacist for one. • Epivir can be taken with or without food. • To ensure that you get a correct dose measure the liquid forms of Epivir with a special dose-measuring spoon or cup not with a regular table spoon. If you do not have a dose-measuring device ask your pharmacist for one. • Epivir tablets and liquid contain a higher dose of Epivir than Epivir-HBV. Epivir is for treating HIV and Epivir-HBV is for treating hepatitis B. Each time you get a refill of this medication be sure you have received the correct brand to treat your condition. • Treatment of HIV/ AIDS almost always requires using many medicines together. To best treat your condition use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor. • To be sure this medication is helping your condition your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. It is important that you not miss any scheduled visits to your doctor. • Store this medication at room temperature away from moisture and heat. You may keep the oral solution (liquid) in the refrigerator but do not let it freeze. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for your next dose skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose. What happens if I overdose? • Seek emergency medical attention if you think you have used too much of this medicine. The symptoms of a Epivir overdose are not known. What should I avoid while taking Epivir? • Avoid having unprotected sex or sharing needles razors or toothbrushes. Taking this medication will not keep you from passing HIV to other people. Talk with your doctor about safe methods of preventing HIV transmission during sex such as using a condom and spermicide. Sharing drug or medicine needles is never safe even for a healthy person. • Avoid drinking alcohol while taking Epivir. Alcohol may increase the risk of damage to your pancreas or liver. What are the possible side effects of Epivir? • Stop using Epivir and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. • Call your doctor at once if you have any problems with your liver while you are using Epivir. Symptoms to watch for include stomach pain nausea and vomiting low fever lost appetite dark urine clay-colored stools or jaundice (yellowing of the skin or eyes). • Swelling of the pancreas (pancreatitis) may occur during treatment with Epivir especially in children using this medication. Call your doctor right away if you notice any of these symptoms of pancreatitis: sudden and severe pain in the upper middle or left side of your stomach nausea and/ or vomiting fever chills rapid pulse or stomach pain that gets worse after eating or when lying down flat. • Call your doctor at once if you have any of these other serious side effects: lactic acidosis — muscle pain or weakness numb or tingly feeling and nausea with vomiting; signs of a new infection — fever chills body aches flu symptoms; or white patches or sores inside your mouth or on your lips. • Less serious side effects may be more likely to occur. Talk with your doctor if you have any of these side effects: changes in the shape or location of body fat (especially in your arms legs face neck breasts and trunk); sleep problems (insomnia) strange dreams; headache dizziness; or a runny or stuffy nose. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Epivir? • Before taking Epivir tell your doctor if you are also taking zalcitabine (Hivid) or ribavirin (Rebetol Ribasphere Ribavirin Virazole). There may be other drugs that can affect Epivir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor

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What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. 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If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea headache and malaise. What are the possible side effects of Anafranil? • If you experience any of the following serious side effects stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips face or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision severe headache); difficulty urinating; or fever with increased sweating muscle stiffness or severe muscle weakness. • Other less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience drowsiness or dizziness; dry mouth and eyes; constipation; mild tremor; sweating; mild agitation weakness or headache; ringing in the ears; nausea; or loss of weight or appetite. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. 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