Anti Depressants

Imitrex (Sumatriptan)

Anti Depressants » Migraines » Imitrex (Sumatriptan)

Imitrex (Sumatriptan) is a cerebral vasoconstrictor used to relieve migraine headache attacks as they occur. This medicine belongs to a group of medicines also known as 'triptans'. This medicine will not prevent or reduce the number of attacks you experience. This medicine may be used to treat other conditions as determined by your doctor.

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About Imitrex (Sumatriptan):

Product Type: Migraines

Brand name: Imitrex Generic name: Sumatriptan What is the most important information I should know about Imitrex? • Your doctor may want to give your first dose of this medicine in a hospital or clinic setting in case you have serious side effects. • Imitrex is used to treat migraine headaches and cluster headaches. Imitrex will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks. • Do not use Imitrex if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan) tranylcypromine (Parnate) selegiline (Eldepryl Emsam) or phenelzine (Nardil) in the past 14 days. • Before using Imitrex tell your doctor if you have a seizure disorder coronary artery disease or risk factors for coronary artery disease (such as diabetes menopause smoking being overweight having high blood pressure or high cholesterol). • Do not use Imitrex within 24 hours after using any other migraine headache medicines. • After using a Imitrex you must wait one hour before using a second injection. Do not use more than two injections in 24 hours. • Imitrex can cause serious side effects on the heart including heart attack or stroke. Tell your doctor if you have any history of heart or circulation problems. You may not be able to use Imitrex. • Imitrex can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. What is Imitrex? • Imitrex is a headache medicine. It is believed to work by narrowing the blood vessels around the brain. Imitrex also reduces substances in the body that can trigger headache pain nausea sensitivity to light and sound and other migraine symptoms. • Imitrex is used to treat migraine headaches and cluster headaches. • Imitrex will only treat a headache that has already begun. It will not prevent headaches or reduce the number of attacks. • Imitrex may also be used for purposes other than those listed in this medication guide. What should I discuss with my health care provider before using Imitrex? • Imitrex can cause serious side effects on the heart including heart attack or stroke. Tell your doctor if you have any history of heart or circulation problems. You may not be able to use Imitrex. • You should not use Imitrex if you have: heart disease; angina (chest pain); liver disease; blood circulation problems; ischemic bowel disease; history of a heart attack or stroke; high blood pressure; or a headache that is not like other headache you have had. • Do not use Imitrex if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan) tranylcypromine (Parnate) selegiline (Eldepryl Emsam) or phenelzine (Nardil) in the past 14 days. • Do not use Imitrex within 24 hours after using any of the following medicines: ergot medicine such as methysergide (Sansert) ergotamine (Ergostat Medihaler Cafergot Ercaf Wigraine) or dihydroergotamine (D.H.E. Migranal Nasal Spray); or almotriptan (Axert) eletriptan (Relpax) frovatriptan (Frova) naratriptan (Amerge) rizatriptan (Maxalt Maxalt-MLT) or zolmitriptan (Zomig). • Before using Imitrex tell your doctor if you have: epilepsy or other seizure disorder; or coronary artery disease (or risk factors that include diabetes menopause smoking being overweight having high blood pressure or high cholesterol having a family history of coronary artery disease being older than 40 and a man or being a woman who has had a hysterectomy). • You may not be able to use Imitrex or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. • FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. • Your name may need to be listed on a Imitrex pregnancy registry when you start using this medication. • Imitrex can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. • This medicine should not be given to anyone younger than 18 years old. How should I use Imitrex? • Use this medication exactly as it was prescribed for you. Do not use the medication in larger or smaller amounts or use it for longer than recommended by your doctor. • Use Imitrex as soon as you notice headache symptoms or after an attack has already begun. • Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects. • Imitrex comes in a prefilled cartridge to be loaded into an autoinjector syringe. Each cartridge contains only one dose that you will injected into your skin. This medicine comes with patient instructions for injecting it. Do not give yourself an injection if you do not understand these instructions. Ask your doctor or pharmacist if you have questions. • After using an injection: If your headache does not completely go away after the injection call your doctor before using a second Imitrex. If your headache goes away and then comes back you may use a second injection if it has been at least one hour since your first injection. Do not use more than two injections in 24 hours. If your symptoms do not improve contact your doctor before using any more injections. • Contact your doctor if you have more than four headaches in one month (30 days). • Store this medicine at room temperature away from moisture heat and light. What happens if I miss a dose? • Since Imitrex is used as needed it does not have a daily dosing schedule. After using a Imitrex you must wait one hour before using a second injection. Do not use more than two injections in 24 hours. What happens if I overdose? • Seek emergency medical attention if you think you have used too much of this medicine or if anyone else has accidentally injected it. • Symptoms of a Imitrex overdose may include seizure (convulsions) tremors or shaking skin redness breathing problems blue-colored lips or fingernails vision problems watery eyes or mouth and weakness or lack of coordination. What should I avoid while using Imitrex? • Imitrex can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. What are the possible side effects of Imitrex? • Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. • Stop using Imitrex and call your doctor at once if you have any of these serious side effects: severe or ongoing chest pain pounding or uneven heart rate; pain or tightness in your chest jaw or neck; sudden numbness or weakness especially on one side of the body; sudden headache confusion problems with vision speech or balance; sudden and severe stomach pain and bloody diarrhea; seizure (convulsions); or numbness or tingling and a pale or blue-colored appearance in your fingers or toes. • Continue using Imitrex and talk with your doctor if you have any of these less serious side effects: nausea vomiting diarrhea; muscle pain; redness or warmth in your face neck or chest; burning numbness or heavy feeling in any part of your body; sneezing runny nose congestion cough; pain or redness where you injected the medicine; feeling dizzy or sleepy; or drooling or sweating. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Imitrex? • Before using Imitrex tell your doctor if you are using any of the following drugs: antidepressants such as citalopram (Celexa) escitalopram (Lexapro) fluoxetine (Prozac Sarafem) fluvoxamine (Luvox) paroxetine (Paxil) or sertraline (Zoloft); • If you are using any of these drugs you may not be able to use Imitrex or you may need dosage adjustments or special tests during treatment. • There may be other drugs not listed that can affect Imitrex. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

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Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. 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What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. Do not take Anafranil without first talking to your doctor if you are pregnant or could become pregnant during treatment. • Anafranil passes into breast milk and may affect a nursing baby. Do not take Anafranil without first talking to your doctor if you are breast-feeding a baby. How should I take Anafranil? • Take Anafranil exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass (8 oz) of water. • Anafranil may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor's instructions. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Store Anafranil at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Anafranil overdose include seizures confusion drowsiness agitation hallucinations and low blood pressure (dizziness fatigue fainting). What should I avoid while taking Anafranil? • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea headache and malaise. What are the possible side effects of Anafranil? • If you experience any of the following serious side effects stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips face or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision severe headache); difficulty urinating; or fever with increased sweating muscle stiffness or severe muscle weakness. • Other less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience drowsiness or dizziness; dry mouth and eyes; constipation; mild tremor; sweating; mild agitation weakness or headache; ringing in the ears; nausea; or loss of weight or appetite. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. 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