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Anti Depressants » Diabetes » Janumet (Sitagliptin phosphate + Metformin) Janumet (Sitagliptin Phosphate + Metformin) is used for treating type 2 diabetes in certain patients. It is used along with diet and exercise. Janumet works by increasing insulin release. It decreases the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce. Buy Janumet (Sitagliptin phosphate + Metformin) and other Diabetes products online at Medstore. Buy Online at Medstore - Click Here!
About Janumet (Sitagliptin phosphate + Metformin): Product Type: Diabetes Brand name: Janumet. Generic name: Sitagliptin phosphate + Metformin. Janumet (Sitagliptin phosphate + Metformin) is used for: treating type 2 diabetes in certain patients. It is used along with diet and exercise. Janumet (Sitagliptin phosphate + Metformin) is a dipeptidyl peptidase-4 inhibitor and biguanide combination. It works by increasing insulin release. It decreases the amount of sugar that the liver produces and the intestines absorb. It also helps to make your body more sensitive to the insulin that you naturally produce. Do NOT use Janumet (Sitagliptin phosphate + Metformin) if: •you are allergic to any ingredient in Janumet (Sitagliptin phosphate + Metformin) •you have type 1 diabetes •you have congestive heart failure that is treated by medicine •you have a severe infection low blood oxygen levels kidney or liver problems or high blood ketone or acid levels (eg diabetic ketoacidosis) or you are severely dehydrated •you have had a stroke or a recent heart attack or you are in shock •you are 80 years old or older and have not had a kidney function test •you will be having surgery or certain lab procedures. Contact your doctor or health care provider right away if any of these apply to you. Before using Janumet (Sitagliptin phosphate + Metformin): Some medical conditions may interact with Janumet (Sitagliptin phosphate + Metformin). Tell your doctor or pharmacist if you have any medical conditions especially if any of the following apply to you: •if you are pregnant planning to become pregnant or are breast-feeding •if you are taking any prescription or nonprescription medicine herbal preparation or dietary supplement •if you have allergies to medicines foods or other substances •if you have a history of heart problems (eg heart failure) lung or breathing problems thyroid problems stomach or bowel problems (eg blockage paralysis) adrenal or pituitary problems or lactic acidosis •if you have a history of inflammation of the pancreas (pancreatitis) •if you have vomiting diarrhea poor health or nutrition low blood calcium or vitamin B12 levels or anemia or if you are dehydrated •if you have an infection fever recent injury or moderate to severe burns •if you drink alcohol or have a history of alcohol abuse •if you will be having surgery or certain lab procedures •if you take a beta-blocker (eg propranolol). Some MEDICINES MAY INTERACT with Janumet (Sitagliptin phosphate + Metformin). Tell your health care provider if you are taking any other medicines especially any of the following: •Amiloride cimetidine digoxin morphine procainamide quinidine quinine ranitidine triamterene trimethoprim or vancomycin because they may increase the risk of Janumet (Sitagliptin phosphate + Metformin)'s side effects •Calcium channel blockers (eg nifedipine) corticosteroids (eg prednisone) diuretics (eg furosemide hydrochlorothiazide) estrogen hormonal contraceptives (eg birth control pills) insulin isoniazid nicotinic acid phenothiazine (eg chlorpromazine) phenytoin sulfonylureas (eg glipizide) sympathomimetics (eg albuterol pseudoephedrine) or thyroid hormones (eg levothyroxine) because the risk of high or low blood sugar may be increased. This may not be a complete list of all interactions that may occur. Ask your health care provider if Janumet (Sitagliptin phosphate + Metformin) may interact with other medicines that you take. Check with your health care provider before you start stop or change the dose of any medicine. How to use Janumet (Sitagliptin phosphate + Metformin): Use Janumet (Sitagliptin phosphate + Metformin) as directed by your doctor. Check the label on the medicine for exact dosing instructions. •An extra patient leaflet is available with Janumet (Sitagliptin phosphate + Metformin). Talk to your pharmacist if you have questions about this information. •Take Janumet (Sitagliptin phosphate + Metformin) by mouth with food. •Take Janumet (Sitagliptin phosphate + Metformin) on a regular schedule to get the most benefit from it. Taking Janumet (Sitagliptin phosphate + Metformin) at the same times each day will help you remember to take it. •Continue to take Janumet (Sitagliptin phosphate + Metformin) even if you feel well. Do not miss any doses. •If you miss a dose of Janumet (Sitagliptin phosphate + Metformin) take it as soon as possible. If it is almost time for your next dose skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use Janumet (Sitagliptin phosphate + Metformin). Important safety information: •Janumet (Sitagliptin phosphate + Metformin) may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Janumet (Sitagliptin phosphate + Metformin) with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. •Follow the diet and exercise program given to you by your health care provider. •Do not drink large amounts of alcohol while you use Janumet (Sitagliptin phosphate + Metformin). Talk to your doctor or health care provider before you drink alcohol while you use Janumet (Sitagliptin phosphate + Metformin). •Do NOT take more than the recommended dose without checking with your doctor. •Be careful not to become dehydrated especially during hot weather or while you are being active. Dehydration may increase the risk of Janumet (Sitagliptin phosphate + Metformin)'s side effects. •Tell your doctor or dentist that you take Janumet (Sitagliptin phosphate + Metformin) before you receive any medical or dental care emergency care or surgery. •If vomiting or diarrhea occurs you will need to take care not to become dehydrated. Contact your doctor for instructions. •Carry an ID card at all times that says you have diabetes. Check your blood sugar levels as directed by your doctor. If they are often higher or lower than they should be and you take Janumet (Sitagliptin phosphate + Metformin) exactly as prescribed tell your doctor. •Janumet (Sitagliptin phosphate + Metformin) does not usually cause low blood sugar. Low blood sugar may be more likely to occur if you skip a meal exercise heavily or drink alcohol. It may also be more likely if you take Janumet (Sitagliptin phosphate + Metformin) along with certain medicines for diabetes (eg sulfonylureas insulin). It is a good idea to carry a reliable source of glucose (eg tablets gel) to treat low blood sugar. If this is not available you should eat or drink a quick source of sugar like table sugar honey candy orange juice or non-diet soda. This will raise your blood sugar level quickly. Tell your doctor right away if this happens. To prevent low blood sugar eat meals at the same time each day and do not skip meals. •Fever infection injury or surgery may increase your risk for high or low blood sugar levels. If any of these occur check your blood sugar closely and tell your doctor right away. •Janumet (Sitagliptin phosphate + Metformin) may commonly cause stomach upset indigestion nausea vomiting or diarrhea at the beginning of treatment. If you develop unusual or unexpected stomach problems or if you develop stomach problems later during treatment contact your doctor at once. This may be a sign of lactic acidosis.•Lab tests including kidney function liver function fasting blood glucose hemoglobin A1c and complete blood cell counts may be performed while you use Janumet (Sitagliptin phosphate + Metformin). These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments. •Use Janumet (Sitagliptin phosphate + Metformin) with caution in the ELDERLY; they may be more sensitive to its effects. Low blood sugar levels may also be more difficult to recognize in the elderly. •Janumet (Sitagliptin phosphate + Metformin) should be used with extreme caution in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed. •PREGNANCY and BREAST-FEEDING: If you become pregnant contact your doctor. You will need to discuss the benefits and risks of using Janumet (Sitagliptin phosphate + Metformin) while you are pregnant. It is not known if Janumet (Sitagliptin phosphate + Metformin) is found in breast milk. If you are or will be breast-feeding while you use Janumet (Sitagliptin phosphate + Metformin) check with your doctor. Discuss any possible risks to your baby. When used for long periods of time Janumet (Sitagliptin phosphate + Metformin) may not work as well. If your blood sugar has been under control and then becomes hard to manage contact your doctor. Do not change the dose of your medicine without checking with your doctor. Possible side effects of Janumet (Sitagliptin phosphate + Metformin): All medicines may cause side effects but many people have no or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome: •Diarrhea; gas; headache; indigestion; nausea; sore throat; stomach upset; stuffy or runny nose; vomiting; weakness. Seek medical attention right away if any of these SEVERE side effects occur: •Severe allergic reactions (rash; hives; itching; difficulty swallowing or breathing; tightness in the chest; swelling of the mouth face lips or tongue; unusual hoarseness); chest pain or discomfort; dizziness or lightheadedness; fast or difficult breathing; feeling of being unusually cold; fever chills or persistent sore throat; general feeling of being unwell; muscle pain or weakness; red blistered swollen or peeling skin; slow or irregular heartbeat; symptoms of pancreas inflammation (eg severe stomach or back pain with nausea or vomiting stomach tenderness or swelling fast heartbeat); unusual drowsiness; unusual or persistent stomach pain or discomfort; unusual tiredness or weakness. This is not a complete list of all side effects that may occur. If you have questions about side effects contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency please read the Guide to Reporting Problems to FDA. If OVERDOSE is suspected: Symptoms may include: •dizziness or lightheadedness; •fast or difficult breathing; •feeling of being unusually cold; •general feeling of being unwell; •muscle pain or tenderness; •slow or irregular heartbeat; •unusual drowsiness; •unusual stomach discomfort; •unusual weakness or tiredness. Proper storage of Janumet (Sitagliptin phosphate + Metformin): Store Janumet (Sitagliptin phosphate + Metformin) at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat moisture and light. Do not store in the bathroom. Keep Janumet (Sitagliptin phosphate + Metformin) out of the reach of children and away from pets. 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View more Diabetes Anti Depressants: Anafranil (Clomipramine HCI) Anafranil (Clomipramine HCI) is a tricyclic antidepressant used to treat depression and obsessive-compulsive disorder. Buy Anafranil (Clomipramine HCI) and other Anti Depressants products online at Medstore. About Anafranil (Clomipramine HCI): Product Type: Anti Depressants Brand name: Anafranil Generic name: Clomipramine HCI What is the most important information I should know about Anafranil? • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. What is Anafranil? • Anafranil is in a class of drugs called tricyclic antidepressants. Anafranil affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive disorder. • Anafranil is used to relieve symptoms of obsessive-compulsive disorder such as recurrent thoughts or feelings and repetitive actions. • Anafranil may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. Do not take Anafranil without first talking to your doctor if you are pregnant or could become pregnant during treatment. • Anafranil passes into breast milk and may affect a nursing baby. Do not take Anafranil without first talking to your doctor if you are breast-feeding a baby. How should I take Anafranil? • Take Anafranil exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass (8 oz) of water. • Anafranil may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor's instructions. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Store Anafranil at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Anafranil overdose include seizures confusion drowsiness agitation hallucinations and low blood pressure (dizziness fatigue fainting). What should I avoid while taking Anafranil? • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea headache and malaise. What are the possible side effects of Anafranil? • If you experience any of the following serious side effects stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips face or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision severe headache); difficulty urinating; or fever with increased sweating muscle stiffness or severe muscle weakness. • Other less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience drowsiness or dizziness; dry mouth and eyes; constipation; mild tremor; sweating; mild agitation weakness or headache; ringing in the ears; nausea; or loss of weight or appetite. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Anafranil may increase the effects of other drugs that cause drowsiness including other antidepressants alcohol antihistamines sedatives (used to treat insomnia) pain relievers anxiety medicines and muscle relaxants. Tell your doctor about all medicines that you are taking and do not take any other prescription or over-the-counter medicines without first talking to your doctor. • Drugs other than those listed here may also interact with Anafranil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including herbal products. 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