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Anti Depressants » Cancer » Methotrexate Methotrexate is an antimetabolite used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis. This medicine works by interfering with cell growth and by suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function. This medicine may also be used to treat other conditions as determined by your doctor including lupus and psoriatic arthritis. Buy Methotrexate and other Cancer products online at Medstore. Buy Online at Medstore - Click Here!
About Methotrexate: Product Type: Cancer Brand name: Methotrexate What is methotrexate? Methotrexate interferes with the growth of certain cells of the body especially cells that reproduce quickly such as cancer cells bone marrow cells and skin cells. Methotrexate is used to treat certain types of cancer of the breast skin head and neck or lung. Methotrexate is also used to treat severe psoriasis and rheumatoid arthritis. Methotrexate is usually given after other medications have been tried without successful treatment of symptoms. Methotrexate may also be used for other purposes not listed in this medication guide. What is the most important information I should know about methotrexate? Methotrexate can cause serious or life-threatening side effects on your liver lungs kidneys and bone marrow (immune system). Do not take this medication in larger amounts or take it for longer than prescribed. Follow the directions on your prescription label. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have liver disease (especially if caused by alcoholism) a blood cell or bone marrow disorder or if you are breast-feeding a baby. This medication can cause birth defects in an unborn baby. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you are pregnant. Use an effective form of birth control whether you are a man or a woman. Tell your doctor if you or your sexual partner become pregnant during treatment. To be sure this medication is not causing harmful effects your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested. Do not miss any scheduled appointments. There are many other medicines that can interact with methotrexate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you. What should I discuss with my healthcare provider before taking methotrexate? Do not use this medication if you are allergic to methotrexate. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you have: • liver disease; • alcoholism or cirrhosis of the liver; • a blood cell disorder such as anemia (lack of red blood cells) or leukopenia (lack of white blood cells); • a bone marrow disorder; or • if you are breast-feeding a baby. Methotrexate is sometimes used to treat cancer even when patients do have one of the conditions listed above. Your doctor will decide if this treatment is right for you. Before using methotrexate tell your doctor if you are allergic to any drugs or if you have: • kidney disease; • liver disease; • lung disease or pneumonia; • stomach ulcers; • any type of infection; or • if you are receiving radiation treatments. FDA pregnancy category X. Methotrexate can cause birth defects in an unborn baby. Do not use methotrexate to treat psoriasis or rheumatoid arthritis if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Use birth control to prevent pregnancy while you are using methotrexate whether you are a man or a woman. Methotrexate use by either parent may cause birth defects. Before you start taking methotrexate your doctor may want you to have a pregnancy test to make sure you are not pregnant. If you are a man use a condom to keep from causing a pregnancy while you are using methotrexate. Continue using condoms for at least 90 days after your treatment ends. If you are a woman use an effective form of birth control while you are taking methotrexate and for at least one cycle of ovulation after your treatment ends. Do not give this medicine to a child without the advice of a doctor. Older adults may be more likely to have side effects from this medication. How should I take methotrexate? Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts or take it for longer than recommended by your doctor. Follow the directions on your prescription label. You must use the correct dose of methotrexate for your condition. The medication is sometimes taken only once per week. Some people have died after taking methotrexate every day by accident. Ask your doctor if you have any questions about your dose of methotrexate or how often to take it. This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions. It is important to use methotrexate regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. To be sure this medication is not causing harmful effects your blood will need to be tested on a regular basis. Your kidney or liver function may also need to be tested and you may need an occasional liver biopsy. Do not miss any scheduled appointments. Store methotrexate at room temperature away from moisture and heat. What happens if I miss a dose? Call your doctor if you miss a dose of methotrexate. What happens if I overdose? Seek emergency medical attention if you think you have used too much of this medicine. An overdose of methotrexate can be fatal. Overdose symptoms may include pale skin easy bruising or bleeding unusual weakness mouth sores nausea vomiting black or bloody stools coughing up blood or vomit that looks like coffee grounds and urinating less than usual or not at all. What should I avoid while taking methotrexate? Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds) especially if you are being treated for psoriasis. Methotrexate can make your skin more sensitive to sunlight and your psoriasis may worsen. Avoid drinking alcohol while taking methotrexate. Methotrexate side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face lips tongue or throat. Stop using methotrexate and call your doctor at once if you have any of these serious side effects: • dry cough shortness of breath; • diarrhea vomiting white patches or sores inside your mouth or on your lips; • blood in your urine or stools; • urinating less than usual or not at all; • fever chills body aches flu symptoms; • sore throat and headache with a severe blistering peeling and red skin rash; • pale skin easy bruising or bleeding weakness; or • nausea stomach pain low fever loss of appetite dark urine clay-colored stools jaundice (yellowing of the skin or eyes). Less serious side effects may include: • nausea vomiting upset stomach; • dizziness tired feeling; • headache; • bleeding of your gums; or • blurred vision. This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. What other drugs will affect methotrexate? Before taking methotrexate tell your doctor if you are using any of the following drugs: • azathioprine (Imuran); • chloramphenicol (Chloromycetin); • hydroxychloroquine (Plaquenil Quineprox); • retinol tretinoin (Retin-A) isotretinoin (Accutane); • steroids (prednisone and others); • sulfa drugs such as Azulfidine Bactrim or Septra; • phenytoin (Dilantin); • probenecid (Benemid); • tetracycline (Brodspec Panmycin Sumycin Tetracap); • theophylline (Elixophyllin Slo-Bid Theobid Theo-Dur); • gold treatments such as auranofin (Ridura) or aurothioglucose (Solganol); • oral diabetes medications such as acetohexamide (Dymelor) chlorpropamide (Diabinese) glipizide (Glucotrol) glimepiride (Amaryl) or tolbutamide (Orinase); • penicillin antibiotic such as ampicillin (Principen) amoxicillin (Amoxil Trimox) carbenicillin (Geocillin) cloxacillin (Cloxapen) dicloxacillin (Dynapen) nafcillin (Unipen) oxacillin (Bactocill) penicillamine (Cuprimine Depen) or Bee-Pen Pen-Vee K Veetids; • salicylates such as aspirin Disalcid Doan's Pills Dolobid Salflex Tricosal and others; or • NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin Advil) naproxen (Aleve Naprosyn) diclofenac (Voltaren) diflunisal (Dolobid) etodolac (Lodine) flurbiprofen (Ansaid) indomethacin (Indocin) ketoprofen (Orudis) ketorolac (Toradol) mefenamic acid (Ponstel) meloxicam (Mobic) nabumetone (Relafen) piroxicam (Feldene) and others. This list is not complete and there may be other drugs that can interact with methotrexate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins minerals herbal products and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Generic Methotrexate Abitrexate Amethopterin Emtexate Folex Imutrex Methopterin Methylaminopterin Mexate Rheumatrex Trexall Xexate 10mg 100 tabs 10mg 200 tabs 5mg 100 tabs 10mg 40 tabs 5mg 200 tabs 2.5mg 240 tabs 7.5mg 100 tabs 10mg 60 tabs 5mg 40 tabs 2.5mg 480 tabs 7.5mg 200 tabs 10mg 80 tabs 5mg 60 tabs 2.5mg 60 tabs 7.5mg 40 tabs 2.5mg 120 tabs 5mg 80 tabs 2.5mg 90 tabs 7.5mg 60 tabs 7.5mg 80 tabs Methotrexate Methotrexate
View more Cancer Anti Depressants: Anafranil (Clomipramine HCI) Anafranil (Clomipramine HCI) is a tricyclic antidepressant used to treat depression and obsessive-compulsive disorder. Buy Anafranil (Clomipramine HCI) and other Anti Depressants products online at Medstore. About Anafranil (Clomipramine HCI): Product Type: Anti Depressants Brand name: Anafranil Generic name: Clomipramine HCI What is the most important information I should know about Anafranil? • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. What is Anafranil? • Anafranil is in a class of drugs called tricyclic antidepressants. Anafranil affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive disorder. • Anafranil is used to relieve symptoms of obsessive-compulsive disorder such as recurrent thoughts or feelings and repetitive actions. • Anafranil may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. Do not take Anafranil without first talking to your doctor if you are pregnant or could become pregnant during treatment. • Anafranil passes into breast milk and may affect a nursing baby. Do not take Anafranil without first talking to your doctor if you are breast-feeding a baby. How should I take Anafranil? • Take Anafranil exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass (8 oz) of water. • Anafranil may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor's instructions. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Store Anafranil at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Anafranil overdose include seizures confusion drowsiness agitation hallucinations and low blood pressure (dizziness fatigue fainting). What should I avoid while taking Anafranil? • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea headache and malaise. What are the possible side effects of Anafranil? • If you experience any of the following serious side effects stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips face or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision severe headache); difficulty urinating; or fever with increased sweating muscle stiffness or severe muscle weakness. • Other less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience drowsiness or dizziness; dry mouth and eyes; constipation; mild tremor; sweating; mild agitation weakness or headache; ringing in the ears; nausea; or loss of weight or appetite. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Anafranil may increase the effects of other drugs that cause drowsiness including other antidepressants alcohol antihistamines sedatives (used to treat insomnia) pain relievers anxiety medicines and muscle relaxants. Tell your doctor about all medicines that you are taking and do not take any other prescription or over-the-counter medicines without first talking to your doctor. • Drugs other than those listed here may also interact with Anafranil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including herbal products. 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