Anti Depressants

Topamax (Topiramate)

Anti Depressants » Anti Convulsants » Topamax (Topiramate)

Topamax (Topiramate) is an anticonvulsant used with other medicines to control certain types of seizures.

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About Topamax (Topiramate):

Product Type: Anti Convulsants

Brand name: Topamax Generic name: Topiramate What is the most important information I should know about Topamax? • Seek immediate medical attention if you experience blurred vision changes in vision or pain in or around the eyes during treatment with Topamax. These may be early signs of a serious side effect. • Do not stop taking Topamax without first talking to your doctor even if your symptoms have improved. It is important to continue taking Topamax to prevent seizures from recurring. • Carry or wear a medical identification tag to let others know that you are taking Topamax in the case of an emergency. • Use caution when driving operating machinery or performing other hazardous activities. Topamax may cause dizziness or drowsiness. If you experience dizziness or drowsiness avoid these activities. • Alcohol should be avoided while taking Topamax. Alcohol may cause increased sedation or drowsiness. It may also increase the risk of having a seizure. • Unless otherwise directed by your doctor drink several extra glasses of fluid each day during treatment with Topamax to minimize the risk of side effects such as kidney stone formation and metabolic acidosis (a decrease in a certain electrolyte in the body). Additional fluid may be necessary during hot weather vigorous exercise and illness (e.g. fever vomiting diarrhea). • Decreased sweating and high body temperature have been associated with the use of Topamax. These side effects may be dangerous. Avoid becoming overheated in hot weather and during vigorous exercise monitor sweating and drink plenty of fluid to maintain hydration. If sweating is decreased or body temperature is elevated contact your doctor. What is Topamax? • The exact way that Topamax works is unknown. However it is believed that Topamax alters the chemical impulses in the brain that cause seizures. • Topamax is used with other medications to control seizures. Topamax is also used to prevent migraine headaches. • Topamax may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Topamax? • Before taking Topamax tell your doctor if you have kidney disease or a history of kidney stones; have liver disease; have lung or respiratory disease such as asthma emphysema or bronchitis; or need to have surgery. • You may not be able to take Topamax or you may require a dosage adjustment or special monitoring during treatment • Topamax is in the FDA pregnancy category C. This means that it is not known whether Topamax will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or if you could become pregnant during treatment. • It is not known whether Topamax passes into breast milk. Do not take Topamax without first talking to your doctor if you are breast-feeding a baby. How should I take Topamax? • Take Topamax exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose of Topamax with a full glass of water. • The tablets should be swallowed whole. Due to their bitter taste the tablets should not be broken. • The capsules may be swallowed whole or opened to facilitate swallowing. If the capsules are opened the entire contents of the capsule should be sprinkled onto a small amount (teaspoon) of soft food (e.g. applesauce custard ice cream oatmeal pudding yogurt). This drug/ food mixture should be swallowed immediately without chewing. The mixture should not be stored for future use. If the mixture is combined in a small container add some water to the container after the dose has been taken and drink the water to ensure the whole dose has been taken. • Topamax can be taken with or without food. • It is important to take Topamax regularly to get the most benefit. • Carry or wear a medical identification tag to let others know that you are taking this medicine in the case of an emergency. • Do not stop taking Topamax without first talking to your doctor even if your symptoms have improved. It is important to continue taking Topamax to prevent seizures from recurring. • Unless otherwise directed by your doctor drink several extra glasses of fluid each day during treatment with Topamax to minimize the risk of side effects such as kidney stone formation and metabolic acidosis (a decrease in a certain electrolyte in the body). Additional fluid may be necessary during hot weather vigorous exercise and illness (e.g. fever vomiting diarrhea). • Your doctor may want you to have blood tests or other medical evaluations during treatment with Topamax to monitor progress and side effects. • Store Topamax at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However if it is almost time for the next dose skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical treatment if an overdose is suspected. • Symptoms of a Topamax overdose are not known but may include severe drowsiness poor coordination tremor confusion difficulty speaking and nausea. What should I avoid while taking Topamax? • Use caution when driving operating machinery or performing other hazardous activities. Topamax may cause dizziness or drowsiness. If you experience dizziness or drowsiness avoid these activities. • Alcohol should be avoided while taking Topamax. Alcohol may cause increased sedation or drowsiness. It may also increase the risk of having a seizure. • Unless otherwise directed by your doctor drink several extra glasses of fluid each day during treatment with Topamax to minimize the risk of side effects such as kidney stone formation and metabolic acidosis (a decrease in a certain electrolyte in the body). Additional fluid may be necessary during hot weather vigorous exercise and illness (e.g. fever vomiting diarrhea). • Ketogenic diets (high protein very low carbohydrate diets that may induce ketosis) may increase the risk of kidney stone formation and should be avoided during treatment with Topamax. • Decreased sweating and high body temperature have been associated with the use of Topamax. These side effects may be dangerous. Avoid becoming overheated in hot weather and during vigorous exercise monitor sweating and drink plenty of fluid to maintain hydration. If sweating is decreased or body temperature is elevated contact your doctor. • Tell your doctor and dentist that you are taking Topamax before having any type of surgery. What are the possible side effects of Topamax? • Seek immediate medical attention if you experience blurred vision changes in vision or pain in or around the eyes during treatment with Topamax. These may be early signs of a serious side effect. • If you experience any of the following serious side effects stop taking Topamax and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips tongue or face; or hives); worsening of seizures; metabolic acidosis (a high acidity of the blood that may be detected by blood tests). Symptoms of metabolic acidosis include increased rate of breathing decreased appetite and irregular heartbeats; decreased sweating; fever or increased body temperature; or side or low back pain or painful or difficult urination (may indicate kidney stones). • Other less serious side effects may be more likely to occur. Continue to take Topamax and talk to your doctor if you experience dizziness poor coordination sluggishness or drowsiness; irregular back-and-forth movements of the eyes; nausea decreased appetite or weight loss; tremor numbness or tingling; confusion difficulty concentrating or decreased memory; speech or language difficulties; or changes in behavior depression nervousness or agitation. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Topamax? • Before taking Topamax tell your doctor if you are taking any of the following medicines: another seizure medication such as valproic acid (Depakote Depakene) carbamazepine (Tegretol Carbatrol Epitol) phenytoin (Dilantin) and others; a carbonic anhydrase inhibitor such as acetazolamide (Diamox) methazolamide (Neptazane) or dichlorphenamide (Daranide); metformin (Glucophage Fortamet); or digoxin (Lanoxin Lanoxicaps). • You may not be able to take Topamax or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the drugs listed above. • Topamax may decrease the effectiveness of certain birth control pills. Talk to your doctor about other birth control options to prevent unintended pregnancy. • Topamax may increase the effects of other drugs that cause drowsiness including antidepressants alcohol antihistamines pain relievers sedative (sleep aids) anxiety medicines and muscle relaxants. Dangerous sedation dizziness or drowsiness may occur if Topamax is taken with any of these medications. • Drugs other than those listed here may also interact with Topamax. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins minerals and herbal products.

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What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. 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If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea headache and malaise. 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