Anti Depressants

Anti Depressants

Anti Depressants
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Zelnorm (Tegaserod)

Anti Depressants » Gastrointestinal » Zelnorm (Tegaserod)

Zelnorm (Tegaserod) is a selective serotonin receptor agonist used to treat irritable bowel syndrome (IBS) in women who have constipation as their main symptom. It may also be used in some patients to treat certain forms of chronic constipation or other conditions as determined by your doctor.

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About Zelnorm (Tegaserod):

Product Type: Gastrointestinal

Brand name: Zelnorm Generic name: Tegaserod What is zelnorm? Tegaserod was withdrawn from the U.S. market on March 30 2007. Tegaserod increases the action of serotonin (a body chemical) in the intestines. This speeds the movement of stools (bowel movements) through the bowels. Tegaserod is used to treat severe chronic irritable bowel syndrome (IBS) in women who have constipation as their main bowel problem (constipation-predominant). It is also used to treat chronic idiopathic constipation in patients less than 65 years of age. Tegaserod has not been shown to be helpful for men with irritable bowel syndrome. Tegaserod may also be used for purposes other than those listed in this medication guide. What is the most important information I should know about zelnorm? Tegaserod was withdrawn from the U.S. market on March 30 2007. Stop taking zelnorm and contact your doctor if you experience new or increased stomach pain or blood in your stool. Diarrhea is an occasional side effect of zelnorm. Most often diarrhea has been reported during the first week of starting zelnorm. Typically diarrhea diminishes with continued therapy. If severe diarrhea or diarrhea together with bad cramping abdominal pain lightheadedness fainting or dizziness develops stop taking zelnorm and contact your doctor. In studies patients receiving zelnorm had more abdominal surgery than patients receiving sugar pills. However it is not known if zelnorm will increase the risk of abdominal surgery. If you suddenly get different or worse abdominal pain contact your doctor. What should I discuss with my healthcare provider before taking zelnorm? Before taking zelnorm tell your doctor if you have • diarrhea or if diarrhea is your main symptom of IBS; • gallbladder problems; • a bowel obstruction abdominal adhesions or sphincter of Oddi dysfunction; or • kidney disease; or • liver disease. You may not be able to take zelnorm or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Stop taking zelnorm and contact your doctor if you experience new or increased stomach pain or blood in your stool. Diarrhea is an occasional side effect of zelnorm. Most often diarrhea has been reported during the first week of starting zelnorm. Typically diarrhea diminishes with continued therapy. If severe diarrhea or diarrhea together with bad cramping abdominal pain lightheadedness fainting or dizziness develops stop taking zelnorm and contact your doctor. Tegaserod is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take zelnorm without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether zelnorm passes into breast milk. Do not take zelnorm without first talking to your doctor if you are breast-feeding a baby. Tegaserod has not been shown to be helpful for men with irritable bowel syndrome. How should I take zelnorm? Take zelnorm exactly as directed by your doctor. If you do not understand these instructions ask your pharmacist nurse or doctor to explain them to you. Take each dose with a full glass of water. Tegaserod should be taken twice a day on an empty stomach shortly before you eat a meal or as your doctor prescribes it. Tegaserod does not improve the symptoms of IBS for everyone. When zelnorm is beneficial it helps to reduce pain and discomfort in the abdominal area bloating and constipation. Some or all symptoms may improve within one to two weeks. If you do not see any improvement in your symptoms after 4 to 6 weeks talk to your doctor. Tegaserod is not a cure for irritable bowel syndrome. If you stop taking zelnorm symptoms may return within 1 or 2 weeks. It is important to take zelnorm regularly to get the most benefit. Store zelnorm at room temperature away from moisture and heat. What happens if I miss a dose? If you miss a dose skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? Seek emergency medical attention. Symptoms of a zelnorm overdose may include diarrhea headache abdominal pain flatulence nausea and vomiting. What should I avoid while taking zelnorm? There are no restrictions on food beverages or activity while taking zelnorm unless otherwise directed by your doctor. Tegaserod side effects If you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives) to zelnorm stop taking this medication and seek emergency medical attention. Stop taking zelnorm and contact your doctor if you experience new or increased stomach pain or blood in your stool. Diarrhea is an occasional side effect of zelnorm. Most often diarrhea has been reported during the first week of starting zelnorm. Typically diarrhea diminishes with continued therapy. If severe diarrhea or diarrhea together with bad cramping abdominal pain lightheadedness fainting or dizziness develops stop taking zelnorm and contact your doctor. In studies patients receiving zelnorm had more abdominal surgery than patients receiving sugar pills. However it is not known if zelnorm will increase the risk of abdominal surgery. If you suddenly get different or worse abdominal pain contact your doctor. Other less serious side effects may be more likely to occur. Continue to take zelnorm and talk to your doctor if you experience • headache dizziness or migraine; • back pain or joint pain; or • abdominal pain nausea or flatulence (gas). Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect zelnorm? Other drugs may interact with zelnorm. Talk your doctor and pharmacist before taking any prescription or over-the-counter medicines including herbal products.

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Anti Depressants: Anafranil (Clomipramine HCI) Anafranil (Clomipramine HCI) is a tricyclic antidepressant used to treat depression and obsessive-compulsive disorder. Buy Anafranil (Clomipramine HCI) and other Anti Depressants products online at Medstore. About Anafranil (Clomipramine HCI): Product Type: Anti Depressants Brand name: Anafranil Generic name: Clomipramine HCI What is the most important information I should know about Anafranil? • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. What is Anafranil? • Anafranil is in a class of drugs called tricyclic antidepressants. Anafranil affects chemicals in the brain that may become unbalanced and cause obsessive-compulsive disorder. • Anafranil is used to relieve symptoms of obsessive-compulsive disorder such as recurrent thoughts or feelings and repetitive actions. • Anafranil may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. This concern about the increased risk of suicidal thoughts or behaviors may be greater if you are 18 years of age or younger and are taking Anafranil. In patients younger than 18 years the period of risk may extend beyond start of therapy or when doses are changed. Your doctor may want you to monitor for the following symptoms: anxiety panic attacks difficulty sleeping irritability hostility impulsivity severe restlessness and mania (mental and/ or physical hyperactivity). These symptoms may be associated with the development of worsening symptoms of depression and/ or suicidal thoughts or actions. Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with Anafranil. Do not stop taking Anafranil. • Anafranil is in the FDA pregnancy category C. This means that it is not known whether Anafranil will harm an unborn baby. Do not take Anafranil without first talking to your doctor if you are pregnant or could become pregnant during treatment. • Anafranil passes into breast milk and may affect a nursing baby. Do not take Anafranil without first talking to your doctor if you are breast-feeding a baby. How should I take Anafranil? • Take Anafranil exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass (8 oz) of water. • Anafranil may be taken several times a day or in one daily dose (usually at bedtime). Follow your doctor's instructions. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • It may be 4 weeks or more before you start to feel better but do not stop taking Anafranil without first talking to your doctor. • Store Anafranil at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. If it is almost time for the next regularly scheduled dose skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor. What happens if I overdose? • Seek emergency medical attention. • Symptoms of a Anafranil overdose include seizures confusion drowsiness agitation hallucinations and low blood pressure (dizziness fatigue fainting). What should I avoid while taking Anafranil? • Use caution when driving operating machinery or performing other hazardous activities. Anafranil may cause drowsiness or dizziness. If you experience drowsiness or dizziness avoid these activities. • Dizziness is likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall. • Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Anafranil. • Grapefruit and grapefruit juice may interact with Anafranil. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Do not stop taking Anafranil suddenly. This could cause symptoms such as nausea headache and malaise. What are the possible side effects of Anafranil? • If you experience any of the following serious side effects stop taking Anafranil and contact your doctor immediately or seek emergency medical treatment: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips face or tongue; or hives); seizures; a fast or irregular heartbeat; a heart attack; high blood pressure (blurred vision severe headache); difficulty urinating; or fever with increased sweating muscle stiffness or severe muscle weakness. • Other less serious side effects may be more likely to occur. Continue to take Anafranil and talk to your doctor if you experience drowsiness or dizziness; dry mouth and eyes; constipation; mild tremor; sweating; mild agitation weakness or headache; ringing in the ears; nausea; or loss of weight or appetite. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Anafranil may increase the effects of other drugs that cause drowsiness including other antidepressants alcohol antihistamines sedatives (used to treat insomnia) pain relievers anxiety medicines and muscle relaxants. Tell your doctor about all medicines that you are taking and do not take any other prescription or over-the-counter medicines without first talking to your doctor. • Drugs other than those listed here may also interact with Anafranil. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including herbal products. 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