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Zocor (Simcard)

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Zocor (Simcard) is an hmg-coa reductase inhibitor or 'statin' used to lower bad cholesterol (LDL) and triglyceride levels in your blood or to raise good cholesterol (HDL) levels in adults. This medicine is used in combination with a low-cholesterol and low-fat diet. Simvastatin may also be used in certain adolescent patients age 10 to 17 years who have a genetically caused cholesterol problem. This medicine works by blocking an enzyme that is necessary for your body to make cholesterol. When this enzyme is blocked your body makes less cholesterol. Keeping your cholesterol level under control may reduce your risk of heart problems and stroke. This medicine is not a cure for high cholesterol but may help to control it. This medicine may also be used to treat other conditions as determined by your doctor.

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About Zocor (Simcard):

Product Type: Cholesterol

Brand name: Zocor Generic name: Simcard What is the most important information I should know about Zocor? • Rare cases of muscle problems and liver problems have been associated with the use of Zocor and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain tenderness or weakness especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes abdominal pain unexplained fatigue dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems. • Do not take Zocor without first talking to your doctor if you have liver disease. • Alcohol and Zocor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. • Do not take Zocor if you are pregnant could become pregnant during treatment or if you are breast-feeding a baby. What is Zocor? • Zocor is an HMG CoA reductase inhibitor. Zocor blocks the production of cholesterol (a type of fat) in the body. • Zocor is used to reduce the total amounts of cholesterol LDL (bad) cholesterol triglycerides (another type of fat) and apolipoprotein B (a protein needed to make cholesterol) in your blood. Zocor (Zocor) is also used to increase the level of HDL (good) cholesterol in your blood. These actions may reduce the risk of hardening of the arteries which can lead to heart attacks stroke and peripheral vascular disease. • Zocor may also be used for purposes other than those listed in this medication guide. What should I discuss with my healthcare provider before taking Zocor? • Do not take Zocor without first talking to your doctor if you have liver disease. • Before taking Zocor tell your doctor if you have kidney disease drink alcoholic beverages have a chronic muscular disease or have a blood disorder. • You may not be able to take Zocor or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. • Zocor is in the FDA pregnancy category X. This means that Zocor is known to cause birth defects if it is taken during pregnancy. Do not take Zocor if you are pregnant or could become pregnant during treatment. • It is not known whether Zocor passes into breast milk. Do not take Zocor without first talking to your doctor if you are breast-feeding a baby. How should I take Zocor? • Take Zocor exactly as directed by your doctor. If you do not understand these directions ask your pharmacist nurse or doctor to explain them to you. • Take each dose with a full glass of water. • For the greatest effect Zocor is usually taken at bedtime or with an evening meal. Follow your doctor's instructions. • Your doctor may want to monitor your liver function with blood tests before starting treatment with Zocor and every six months after both the start of your treatment and any increase in dose. Depending on the results of these tests your doctor can determine how much monitoring you will require. • Grapefruit and grapefruit juice may interact with Zocor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Eat a low-fat low-cholesterol diet. To realize beneficial effects from Zocor avoid fatty high-cholesterol foods. • It is important to take Zocor regularly to get the most benefit. • Do not stop taking Zocor without first talking to your doctor. Zocor may need to be taken on a long-term basis for the treatment of high cholesterol. • Your doctor may want you to have blood tests or other medical evaluations during treatment with Zocor to monitor progress and side effects. • Store Zocor at room temperature away from moisture and heat. What happens if I miss a dose? • Take the missed dose as soon as you remember. However if it is almost time for the next dose skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication. What happens if I overdose? • Seek emergency medical attention if an overdose is suspected. • Symptoms of a Zocor overdose include nausea diarrhea stomach distress and indigestion. What should I avoid while taking Zocor? • Grapefruit and grapefruit juice may interact with Zocor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. • Alcohol and Zocor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined. What are the possible side effects of Zocor? • Rare cases of muscle problems and liver problems have been associated with the use of Zocor and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain tenderness or weakness especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes abdominal pain unexplained fatigue dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems. • If you experience any of the following serious side effects stop taking Zocor and seek emergency medical attention or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips tongue or face; or hives); decreased urine or rust-colored urine; or blurred vision. • Other less serious side effects may be more likely to occur. Continue to take Zocor and talk to your doctor if you experience gas bloating nausea stomach upset heartburn abdominal pain constipation or diarrhea; cough; headache; or insomnia. • Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. What other drugs will affect Zocor? • Do not take Zocor without first talking to your doctor if you are taking any of the following medicines: cyclosporine (Sandimmune Neoral); gemfibrozil (Lopid) clofibrate (Atromid-S) or fenofibrate (Tricor); niacin (Nicolar Nicobid Slo-Niacin others); erythromycin (E-Mycin E.E.S. Ery-Tab others) or clarithromycin (Biaxin); cholestyramine (Questran) or colestipol (Colestid); an antifungal medication such as itraconazole (Sporanox) fluconazole (Diflucan) or ketoconazole (Nizoral); nefazodone (Serzone); digoxin (Lanoxin Lanoxicaps); warfarin (Coumadin); a protease inhibitor such as amprenavir (Agenerase) indinavir (Crixivan) nelfinavir (Viracept) ritonavir (Norvir) lopinavir-ritonavir (Kaletra) or saquinavir (Invirase Fortovase); amiodarone (Cordarone Pacer one); or verapamil (Calan Covera-HS Isoptin Verelan). • You may not be able to take Zocor or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above. • Drugs other than those listed here may also interact with Zocor. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins minerals and herbal products.

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What should I discuss with my healthcare provider before taking Anafranil? • Do not take Anafranil if you have taken a monoamine oxidase inhibitor such as isocarboxazid (Marplan) phenelzine (Nardil) or tranylcypromine (Parnate) within the last 14 days. • Before taking Anafranil tell your doctor if you have liver disease kidney disease asthma thyroid disease diabetes stomach or intestinal problems high blood pressure or heart disease had a heart attack in the last 6 weeks an enlarged prostate or difficulty urinating glaucoma or seizures. • You may not be able to take Anafranil or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above. • While you are taking Anafranil you may need to be monitored for worsening symptoms of depression and/ or suicidal thoughts at the start of therapy or when doses are changed. 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